Learning in Parkinsonism By Carrot or by Stick : Cognitive Reinforcement
نویسنده
چکیده
www.sciencemag.org (this information is current as of October 8, 2009 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/306/5703/1940 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/1102941/DC1 can be found at: Supporting Online Material http://www.sciencemag.org/cgi/content/full/306/5703/1940#otherarticles , 13 of which can be accessed for free: cites 31 articles This article 153 article(s) on the ISI Web of Science. cited by This article has been http://www.sciencemag.org/cgi/content/full/306/5703/1940#otherarticles 35 articles hosted by HighWire Press; see: cited by This article has been http://www.sciencemag.org/cgi/collection/neuroscience Neuroscience : subject collections This article appears in the following http://www.sciencemag.org/about/permissions.dtl in whole or in part can be found at: this article permission to reproduce of this article or about obtaining reprints Information about obtaining
منابع مشابه
By carrot or by stick: cognitive reinforcement learning in parkinsonism.
To what extent do we learn from the positive versus negative outcomes of our decisions? The neuromodulator dopamine plays a key role in these reinforcement learning processes. Patients with Parkinson's disease, who have depleted dopamine in the basal ganglia, are impaired in tasks that require learning from trial and error. Here, we show, using two cognitive procedural learning tasks, that Park...
متن کاملBy Carrot or by Stick: Cognitive Reinforcement Learning in Parkinsonism Supporting Online Material
Procedures were approved by the HealthONE Institutional Review Board and the University of Colorado Human Research Committee. We tested 30 PD patients and 19 healthy seniors matched for age, education, and scores on the North American Adult Reading Test (NAART), an estimate of premorbid verbal IQ (1). The demographics of seniors and PD patients are shown in Table 1. PD patients were recruited f...
متن کاملEstrogen agonist genistein differentially influences the cognitive and motor disorders in an ovariectomized animal model of Parkinsonism
Objective(s): Parkinson's disease (PD) is a progressive neurological disorder associated with motor disabilities and cognitive dysfunction as well. Evidence indicates that PD occurs less frequently in women than men, confirming a role for steroid hormones in protection of dopaminergic nigrostriatal neurons. It is reported that soy genistein, an estrogen agonist phytoestrogen, display neuroprote...
متن کاملThe sound of change: visually-induced auditory synesthesia
References 1. Niv, Y. (2007). Cost, benefit, tonic, phasic: what do response rates tell us about dopamine and motivation? Ann. NY Acad. Sci. 1104, 357–376. 2. Satoh, T., Nakai, S., Sato, T., and Kimura, M. (2003). Correlated coding of motivation and outcome of decision by dopamine neurons. J. Neurosci. 23, 9913–9923. 3. Brown, P., Chen, C.C., Wang, S., Kühn, A.A., Doyle, L., Yarrow, K., Nuttin,...
متن کاملAn Adaptive Learning Game for Autistic Children using Reinforcement Learning and Fuzzy Logic
This paper, presents an adapted serious game for rating social ability in children with autism spectrum disorder (ASD). The required measurements are obtained by challenges of the proposed serious game. The proposed serious game uses reinforcement learning concepts for being adaptive. It is based on fuzzy logic to evaluate the social ability level of the children with ASD. The game adapts itsel...
متن کامل